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Cytomegalovirus downregulates IRE1 to repress the unfolded protein response.

Cytomegalovirus downregulates IRE1 to repress the unfolded protein response.

July 6, 2025 Category: Blog

During viral infection, a massive demand for viral glycoproteins can overwhelm the capacity of the protein folding and quality control machinery, leading to an accumulation of unfolded proteins in the endoplasmic reticulum (ER).To restore ER homeostasis, cells initiate the unfolded protein response (UPR) by activating three ER-to-nucleus signaling

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Risk in Implementing Building Information Modelling (BIM) in Malaysia Construction Industry: A Review

July 6, 2025 Category: Blog

Building Information Modelling (BIM) terminology in the construction industry has been widespread used as industry standard buzzword term.BIM could open up a broad range of benefits in the construction industry.However, rate of implementation does not match its benefits.Why BIM has not been fully adopted in construction industry? The underlying pro

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